Arthritis, Cell Proliferation - drug effects, Extracellular Signal-Regulated MAP Kinases - metabolism, Cell Cycle - drug effects, Tumor Necrosis Factor-alpha - biosynthesis, Interleukin-1beta - biosynthesis, Synovial Membrane - cytology, Matrix Metalloproteinase 2 - biosynthesis, Matrix Metalloproteinase 9 - biosynthesis, Rheumatoid - pathology, G1 Phase Cel...