MORTALITY, Aquatic ecosystems, Gene expression, Survival, Biomarkers, Populations, Laboratories, Toxicity, Exposure, Copper, Sediments, Organisms, Metabolites, Chemicals, Snails, Change detection, Abundance, mesocosm, Biota, microcosm, chironomids, transsulfuration, copper toxicity, sediment toxicity, cysteine metabolism, metabolomics, Toxicants, Sediment co...