Animals, Caenorhabditis elegans - drug effects, Caenorhabditis elegans - genetics, Caenorhabditis elegans - metabolism, Caenorhabditis elegans Proteins - genetics, Dose-Response Relationship, Drug, Insulin - genetics, Insulin - metabolism, Intestines - drug effects, Mutation, Nanoparticles - chemistry, Nanoparticles - toxicity, Phosphatidylinositol 3-Kinases...